Secunia PSI opens to a white screen then disappears

First thing I would try would be to set this setting on the local exe before making it a global setting.

Go to -> C:\Program Files\Secunia\PSI

Right Click psi.exe -> Click Properties -> Click the Compatibility Tab -> Check "Turn off advanced text services for this program" -> Click Ok

If that didn't work, we are going to set it globally.

Click Start -> Control Panel -> Regional and Language Options -> Languages -> Click Details -> Click Advanced -> Check "Turn off advanced text services"

Launch Secunia and it should load.

Tested with:
Windows XP SP3
Secunia PSI 2.0